Main points

• The purpose of the ANRS Viropreg cohort is to study chronic viral infections and (re)emerging viral infections and the risks associated with exposure to these viruses in pregnant women and their foetuses.
• Initially, the cohort will focus on HIV-1/HIV-2 infection, chronic viral hepatitis and arboviruses in order to assess the risk of mother-to-foetus transmission and the impact of infection on both the course and outcome of pregnancy and on the short- and long-term health of the unborn child. Other more specific issues related to the viral infection in question will also be studied, such as difficulties in accessing care or remaining in the healthcare system, and the impact of social and individual characteristics on the occurrence of viral infections and their consequences.
• Subsequently, depending on the various viral emergences/re-emergences whose impact (of the infection itself and/or its treatment) on (i) the health of the pregnant woman, (ii) the course of pregnancy, and (iii) the health of the unborn child, are still poorly or inadequately characterised (dengue, chikungunya, HTLV-1, etc.), the protocol will be expanded through amendments, initially to include infection with the dengue virus and the Oropouche virus.