Diseases and pathogens

The agency focuses on research into HIV/AIDS, viral hepatitis, sexually transmitted infections, tuberculosis and emerging infectious diseases (in particular viral haemorrhagic fevers, arboviruses and emerging respiratory infections, including Covid-19).

Last updated on 12 March 2025

Understanding and tackling infectious diseases

  • Infectious diseases result from the invasion and proliferation of pathogenic agents-bacteria, viruses, parasites or fungi-in a host. They can be transmitted directly (human-to-human contact, respiratory droplets, biological fluids) or indirectly (vectors, water, contaminated food, inert surfaces).
  • They represent a major public health challenge because of their ability to emerge, spread rapidly and evolve under the pressure of therapeutic and environmental interventions.
  • The study of infectious diseases mobilizes multidisciplinary approaches combining microbiology, immunology, epidemiology and social sciences, in order to understand pathophysiological mechanisms, optimize surveillance strategies and develop effective diagnostic, therapeutic and prophylactic tools.

Discover below the main diseases and pathogens for which ANRS MIE is involved in research projects to improve their understanding, prevention, diagnosis and treatment.



Oropouche

Oropouche virus disease is an arboviral disease actively circulating in several regions of Central and South America and the Caribbean.

Mpox

Mpox (formerly known as monkeypox) is a disease that has been circulating for decades in West and Central Africa.

Arboviruses

Arboviruses (arthropod-borne viruses) are transmitted to humans and/or other vertebrates by certain types of blood-feeding arthropods (mosquitoes, ticks, sandflies and midges). They transmit the pathogen during their blood meal, after having bitten an infected person or animal. Dengue, Zika and…

Avian influenza A (H5N1)

Avian influenza, also known as bird flu or formerly fowl plague, caused by A strains of the influenza virus, is an infectious disease affecting wild and domestic birds.

HIV

The human immunodeficiency virus (HIV), which causes AIDS, affects around 38 million people worldwide, according to the WHO.

COVID-19

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus.

Sexually transmitted infections (STIs)

The majority of sexually transmitted infections (STIs) are caused by bacteria or parasites.

Tuberculosis

Tuberculosis is one of the deadliest infectious diseases. Every day, around 28 000 people contract it and over 4 100 people die from it, according to the WHO.

Viral haemorrhagic fevers

Viral haemorrhagic fevers (VHFs) include various diseases (Ebola, Lassa fever, Marburg fever, Crimean-Congo fever, etc)

Viral hepatitis

Viral hepatitis is inflammation of the liver caused by any of the viruses A, B, C, D and E

Chikungunya

Chikungunya is an infectious disease caused by an arbovirus, the chikungunya virus. Chikungunya can now be found in non-tropical regions, including Europe.

Dengue

Dengue is an infectious disease caused by the dengue virus, an arbovirus. It is the most widespread human arboviral disease in the world.